Optimus Pharma granted permission for Restricted Use under Emergency Situation from the DCGI for its COVID-19 pill MOLNUPIRAVIR
Hyderabad (Telangana) [India], December 28: Hyderabad, Optimus Pharma announced launching of their front line COVID-19 medication Molnupiravir in the Indian market, as they have received permission the restricted emergency use for Covid-19 drug. Optimus Pharma successfully completed the Phase 3 Clinical Trial on 1218 subjects across 29 geographical study sites all over India. “We want to cover maximum demographic diversity into our trial in order to obtain data across the different geographical regions of the country and conclusive evidence that Molnupiravir is able to bring about viral load reduction over 5 days of treatment duration,” said Chairman and Managing Director of Optimus Pharma, Dr D Srinivasa Reddy. Optimus Pharma has developed the API in the house at its R&D centre in Hyderabad. Optimus Pharma has revealed highly promising results of the drug in its ability to reduce viral load and bring out significant symptomatic improvement in patients’ health.
It is to be noted that in the Clinical Trial, Molnupiravir was administered to the subjects along with Standard of Care (SoC) medication as per the approved protocol by CDSCO. The trial was successful in establishing a clinical significant results of ‘Molnupiravir + SoC’ over ‘SoC’ arm.
- Rate of hospitalization was less in Molnupiravir+SoC when compared to SoC group.
- Greater clinical improvement observed in Molnupiravir + SoC arm compared to SOC alone by Day 5 and Day 10.
- Proportion of subjects with RT-PCR negativity at Day 5 and Day 10 was statistically significant in Molnupiravir + SoC arm.
- Higher viral load reduction was observed in Molnupiravir+ SoC arm
- No serious safety concerns observed with Molnupiravir in overall study duration, no mortality was observed in the trial across both the arms
Molnupiravir is administered as an 800 mg dose by orally consuming four capsules of 200mg twice a day. Upon oral administration, Molnupiravir, being a prodrug, is metabolized into its active form and converted into its triphosphate (TP) form. The TP form of Molnupiravir is incorporated into RNA and inhibits the action of viral RNA-dependent RNA polymerase. This results in the termination of RNA transcription, thereby significantly reducing viral replication.
Optimus Pharma is ready with a commercial quantity of the drug to cater to the unmet medical need of the nation. It is with heartfelt gratitude that we thank the Subject Expert Committee of the CDSCO and the DCGI for their valuable recommendations and guidance for the Clinical Trial, thereby making this project a huge success, said Dr D. Srinivas Reddy (MD Optimus) in his statement to the press. Optimus Pharma is committed to consistently integrating quality, affordability and reliability into their products and ensuring timely access to life-saving medication to whomsoever is in need.
Nice post. I learn something new and challenging on websites I stumbleupon on a daily basis.
It’s always helpful to read through content from other authors and practice something from other sites.
Wow, awesome blog format! How long have you been running a blog for?
you made blogging look easy. The whole look of your website is magnificent, let alone the
content material!
Hi friends, its enormous piece of writing concerning teachingand completely explained,
keep it up all the time.
Thanks for your personal marvelous posting!
I really enjoyed reading it, you happen to be a great author.I will make sure to bookmark your blog and
will eventually come back from now on. I want to encourage that you continue your great
work, have a nice evening!
Wow that was strange. I just wrote an really long comment but after I clicked submit my comment didn’t show up.
Grrrr… well I’m not writing all that over again. Anyhow, just wanted to say fantastic
blog!
Simply wish to say your article is as astounding.
The clearness on your publish is simply nice and i can think you’re knowledgeable in this subject.
Well together with your permission let me to take hold of
your feed to stay up to date with drawing close post.
Thanks 1,000,000 and please carry on the gratifying work.
Hello there I am so glad I found your blog page, I really found
you by mistake, while I was searching on Digg for something else, Regardless I am here now and would just like to say thanks a lot
for a tremendous post and a all round entertaining blog (I also love the theme/design),
I don’t have time to browse it all at the minute but I have saved it
and also added in your RSS feeds, so when I have time I
will be back to read a lot more, Please do keep up the fantastic work.
I’m not that much of a internet reader to be honest but your blogs
really nice, keep it up! I’ll go ahead and bookmark your site to come
back down the road. Cheers
Hello There. I found your weblog the usage of msn. This is
a really smartly written article. I will make sure to bookmark it and return to read extra of your helpful info.
Thank you for the post. I will certainly return.
I’m not sure exactly why but this website is loading
extremely slow for me. Is anyone else having this problem or is it a problem on my end?
I’ll check back later and see if the problem still exists.
Wow that was unusual. I just wrote an incredibly long comment but after I clicked submit my comment didn’t show up.
Grrrr… well I’m not writing all that over again. Anyways, just wanted
to say excellent blog!
Hi there, I discovered your blog via Google while looking for a similar topic, your site came up, it seems to be good.
I have bookmarked it in my google bookmarks.
Hi there, simply turned into alert to your weblog thru Google, and found
that it is truly informative. I’m gonna watch out for brussels.
I’ll be grateful for those who continue this in future.
Numerous other people will likely be benefited out of your writing.
Cheers!
Here is my homepage – coupon
962293 506577This web site is really a walk-through it truly will be the details you wanted concerning this and didnt know who to inquire about. Glimpse here, and you will totally discover it. 974620
109851 896515Yay google is my world beater assisted me to uncover this wonderful web website ! . 81432